Evaluation of the efficacy of homologous autoinoculation therapy in treatment of multiple recalcitrant warts.

Autor: Abdelmonaem, Nisreen Abbas, shaheen, Maha Adel, Foad, Tamer Mohsen, Elhusseiny, Rania Mahmoud
Předmět:
Zdroj: QJM: An International Journal of Medicine; 2021 Supplement, Vol. 114, pi100-i101, 2p
Abstrakt: Background: Warts are infections caused by human papillomavirus (HPV). There are new trends towards the use of immunotherapy in treatment of warts. Homologous autoinoculation is a minimally invasive procedure, which treats warts by stimulating a specific immune response against HPV Objective: To evaluate the efficacy of autoinoculation therapy in treatment of multiple recalcitrant warts. Methods: Under local anesthesia and aseptic condition, inoculum was collected by paring a wart by scalpel and by pressing it between two sterile glass slides. After making a subcutaneous Pocket in non-dominant forearm, the inoculum was introduced in the subcutaneous pocket with forceps and dressed. Follow up for 1,2,12 and 16 weeks was done. Results: Forty patients were included. At 12 weeks of therapy 42.5% showed complete clearance, 27.5% showed moderate clearance, 15% showed mild clearance and 12.5% showed treatment failure. No significant complication was documented after 1 and 2 weeks of follow up except in 3 patients in form of mild inflammation and mild pain. There was no recurrence at16 weeks follow up session. Conclusion: Autoinoculation is simple and effective method in treatment of different types of warts including genital wart. It also prevents recurrence. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index