| Autor: |
Nardangeli, Nolan, Thomson, Jared, Topolovčan, Nikola, Hudlický, Tomáš |
| Předmět: |
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| Zdroj: |
Synthesis; 2021, Vol. 53 Issue 21, p4110-4116, 7p |
| Abstrakt: |
A 7-step total synthesis of methyl 1,5,8-trimethoxy-1 H -isochromene-3-carboxylate and a 5-step synthesis of its C-3 derivatives are reported. Sonogashira coupling of 2-halobenzaldehydes with terminal acetylenes was employed to access 2-alkynylbenzaldehydes, which underwent a Pd-catalyzed annulation to afford the corresponding isochromene-containing products. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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