| Autor: |
Brun, Emilie Marie Sophie Patit-Tha, Calvert, Nicholas David, Suchý, Mojmír, Kirby, Alexia, Melkus, Gerd, Garipov, Ruslan, Addison, Christina L., Shuhendler, Adam J. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 10/25/2021, Vol. 57 Issue 83, p10867-10870, 4p |
| Abstrakt: |
A new CEST-MRI contrast agent, 2-HYNIC, capable of sensing aromatic aldehydes is reported. Pyridoxal 5′-phosphate, a key Vitamin B6 metabolite necessary for >140 biotransformations was mapped by CEST-MRI in vitro and in vivo in lung cancer. 2-HYNIC provided access to this key biomarker associated with a variety of human diseases. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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