| Autor: |
Kazaryan, Sh. A., Rshtuni, L. R., Hovhannisyan, A. A. |
| Zdroj: |
Biophysics; Jul2021, Vol. 66 Issue 4, p623-628, 6p |
| Abstrakt: |
The emergence of antibiotic-resistant bacterial strains leads to the need to find new antibacterial agents. Due to their properties, silver nanoparticles and plant extracts are more often considered as promising antibacterial agents. The aim of this work was to study the antibacterial properties of silver nanoparticles and evaluate the potential effects of the combination of silver nanoparticles and Teucrium polium extract. In this study, we investigated the antibacterial activity of silver nanoparticles and a 96% ethanol extract of T. polium against wild-type strains of E. coli K-12 DSM 1116 and S. aureus MDC 5233. The results showed that the plant extract and silver nanoparticles have antibacterial effects. The T. polium 70% ethanol extract had no antibacterial effect, but provided an increase in the antibacterial activity of silver nanoparticles (by 4.5 times against E. coli K-12 and by 2 times against S. aureus). The 96% ethanol extract made it possible to increase the antibacterial activity of silver nanoparticles against E. coli K-12 by 4.2 times and S. aureus by 6.6 times. Thus, the synergistic antibacterial effect between the extract and nanoparticles, which might be due to different mechanisms of action of the constituents, was observed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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