Optoacoustic imaging using interferometric measurement of surface displacement.

Autor: Carp, Stefan A., Guerra III, Arnold, Duque Jr., Samuel Q., Venugopalan, Vasan
Předmět:
Zdroj: Applied Physics Letters; 12/6/2004, Vol. 85 Issue 23, p5772-5774, 3p, 1 Diagram, 2 Graphs
Abstrakt: We describe an optoacoustic imaging technique based on time-resolved measurements of laser-induced thermoelastic expansion. Tomographic images of tissue phantoms are formed using such measurements made at several locations following irradiation with a Q-switched Nd:YAG (λ=1064 nm) laser pulse. Our system is based on a modified Mach–Zehnder interferometer that measures surface displacement with a temporal resolution of 4 ns and a displacement sensitivity of 0.3 nm. Images formed from data sets acquired from several highly scattering tissue phantoms provide better than 200 μm resolution and show great promise for high-resolution noninvasive imaging of heterogeneous tissues at depths approaching 1 cm. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index