Neurological Manifestations Associated with Parvovirus B19 Infection in Immunocompetent Children: Case Series and Systematic Review.

Autor: Monteiro, Vinícius Silva, Baía-da-Silva, Djane Clarys, Silva, Valderjane Aprigio, João, Guilherme Augusto Pivoto, Marinho, Eveny Perlize Melo, Cubas-Vega, Nadia Carolina, Val, Fernando Fonseca Almeida, Perez-Gomez, Aline Stephanie, Monte, Rossiclea Lins, Mota, Adolfo, Lacerda, Marcus Vinícius Guimarães, Bastos, Michele Souza, Pivoto João, Guilherme Augusto, Souza Bastos, Michele
Předmět:
Zdroj: Journal of Tropical Pediatrics; Aug2021, Vol. 67 Issue 4, p1-9, 9p
Abstrakt: An increasing number of reports have described human parvovirus B19 infection in association with a variety of neurological manifestations, especially in children. This study assessed the clinical and laboratory outcomes found in a case series of immunocompetent children who tested positive for parvovirus B19 by qualitative polymerase chain reaction assays of cerebrospinal fluid, in a tertiary referral center in the western Brazilian Amazon. We screened 178 children with clinically diagnosed central nervous system infections (meningoencephalitis). Of these, five (2.8%) were positive for parvovirus B19. A literature review also presented herein identified a further 50 cases of parvovirus B19 with neurological manifestations. Thus, even if the classic signs of parvovirus B19 infection are absent, such as the well-known rash, children with signs of neurological infection should also be evaluated for parvovirus B19 infection. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index