Pulmonary Large Cell Neuroendocrine Carcinoma Associated With Lambert-Eaton Syndrome.

Autor: Hernandez-Arriaga, Pamela, Gonzalez-Urquijo, Mauricio, López Altamirano, Daniel Fernando, Vaca-Cartagena, Bryan, Vergil-Vargas, Andres, Rios-Pascual, Silviano, Perez-Saucedo, Jose Eduardo, Sepúlveda-Malec, Ricardo
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Zdroj: Clinical Pathology; 10/11/2021, Vol. 14, p1-4, 4p
Abstrakt: Lambert-Eaton syndrome is a rare paraneoplastic disorder of the neuromuscular junction, characterized by impaired release of acetylcholine, which causes proximal muscle weakness, depressed tendon reflexes, and autonomic changes. Most cases of Lambert-Eaton syndrome present in small-cell lung carcinoma, and only a few cases have been reported in other lung subtypes. Herein, we report a case of 69 years old male patient with Lambert-Eaton syndrome as a rare association with a pulmonary large-cell neuroendocrine carcinoma, which presented 5 months before neoplasm diagnosis. A lobectomy was auspiciously performed. A review of the literature is also presented. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index