Ocular adnexal marginal zone lymphoma arising in a patient with IgG4-related ophthalmic disease.

Autor: Kenji Nishida, Yuka Sogabe, Ayako Makihara, Akemi Senoo, Hisanori Morimoto, Mai Takeuchi, Yuka Gion, Tadashi Yoshino, Yasuharu Sato
Předmět:
Zdroj: Modern Rheumatology; 2019, Vol. 29 Issue 2, p383-387, 5p
Abstrakt: A 41-year-old man was diagnosed with immunoglobulin G4-related disease (IgG4-RD) in both eyelids 4 years ago and exhibited good response to steroid therapy. However, rapid swelling of the right eyelid lesion was recently observed. As IgG4-RD progression was suspected, biopsy was performed. Although the histology was consistent with IgG4-RD, the infiltrating large atypical lymphoid cells showed immunoglobulin light-chain restriction and IgH gene rearrangement. Consequently, he was diagnosed with extranodal marginal zone lymphoma with abundant IgG4-positive cells. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index