| Autor: |
Satoshi Morinaka, Hiroto Tsuboi, Shinya Hagiwara, Toshiki Sugita, Daiki Tabuchi, Ryota Sato, Taihei Nishiyama, Shota Okamoto, Toshihiko Terasaki, Mizuki Yagishita, Hiroyuki Takahashi, Yuya Kondo, Isao Matsumoto, Takayuki Sumida |
| Předmět: |
|
| Zdroj: |
Modern Rheumatology; Nov2021, Vol. 31 Issue 6, p1129-1134, 6p |
| Abstrakt: |
Objectives: We compared large vessel vasculitis (LVV) clinical features between age groups. Methods: We retrospectively examined clinical features and therapies in 41 LVV patients at our hospital from January 2010 to March 2020. We compared two patient groups, elderly (≥50 years) and young (<50 years). Results: Of all patients, 29 were elderly and 12 were young. In the younger group, upper extremity symptoms (p <.05), bruits (p <.01), and cardiovascular complications (p <.01) were more common. Of the elderly group, 7 (24%) met classification criteria for giant cell arteritis while none of the younger group met these criteria; however, 10 (83%) of the younger group and 3 (10%) of the elderly group met the ACR classification criteria for Takayasu arteritis (p <.01). In the elderly group, 16 patients (66%) met no criteria (p <.01). There were no significant differences in laboratory findings but imaging showed a significantly higher incidence of head and neck artery lesions in the younger group (p <.05). The younger group was more likely to receive additional tocilizumab (p <.01) and cardiovascular complications were more likely to occur in younger patients (p < .01). Conclusion: LVV clinical features differed between elderly- and young-age-onset groups. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
