| Autor: |
Berhane, Ilyas A., Burde, Ameya S., Kennedy-Ellis, Jonathan J., Zurek, Eva, Chemler, Sherry R. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 10/7/2021, Vol. 57 Issue 78, p10099-10102, 4p |
| Abstrakt: |
The enantioselective copper-catalyzed oxidative coupling of alkenols with styrenes for the construction of dihydropyrans, isochromans, pyrans and morpholines is reported. A concise formal synthesis of a σ1 receptor ligand using this alkene carboetherification methodology was demonstrated. Ligand, solvent and base all impact reaction efficiency. DFT transition state calculations are presented. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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