| Autor: |
Tsuboi, Kazuto, Yano, Fumiaki, Omura, Nobuo, Hoshino, Masato, Yamamoto, Se-Ryung, Akimoto, Shunsuke, Masuda, Takahiro, Sakashita, Yuki, Ikegami, Toru |
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| Zdroj: |
Surgery Today; Oct2021, Vol. 51 Issue 10, p1568-1576, 9p |
| Abstrakt: |
Purpose: To identify the factors that affect laparoscopic fundoplication (LF) treatment efficacy in patients with erosive gastroesophageal reflux disease (e-GERD) esophagitis, based on the findings of multichannel intraluminal impedance pH (MII-pH) and high-resolution manometry (HRM). Methods: The subjects were 102 patients with e-GERD diagnosed by endoscopy, who underwent LF as the initial surgery. To analyze the findings of MII-pH and HRM, the patients were divided into two groups: a cured group (CR), comprised of patients whose esophagitis was cured postoperatively; and a recurrence group (RE), comprised of patients who suffered recurrent esophagitis. Results: There were 96 patients in the CR group and 6 in the RE group. MII-pH indicated that the acid reflux time, the longest reflux time, and the number of refluxes longer than 5 min, were significantly higher in the RE group than in the CR group (p = 0.0028, p = 0.0008, p = 0.012, respectively). The HRM indicated that only the distal contractile integral (DCI) was significantly lower in the RE group (p = 0.0109). Conclusion: The results of this study indicate that esophageal clearance may affect the treatment outcome of LF. Based on the findings of MII-pH, the longest reflux time and the number of refluxes longer than 5 min were important factors influencing the therapeutic effect, whereas based on the HRM, the DCI value was most important. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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