КЛИНИЧНО-ЛАБОРАТОРНА ОЦЕНКА НА ГЕСТАЦИОННАТА ТИРЕОИДНА ФУНКЦИЯ В ПЪРВИ И ВТОРИ ТРИМЕСТЪР.

Autor: Делев, Боян, Денева, Таня, Нончев, Боян, Аргатска, Антоанета, Няголова, Персиана, Митева, Mария
Zdroj: Knowledge: International Journal; 2021, Vol. 47 Issue 4, p569-574, 6p
Abstrakt: To date, much scientific evidence has been accumulated and it is well known that during pregnancy thyroid function undergoes significant changes in the conditions of increased requirements for hormone synthesis and unusual (but physiological) stimulating effects of hCG-human chorionic gonadotropin. These processes are dynamic and are often associated with marked fluctuations in the values of thyroid hormones and TSH-thyroid-stimulating hormone, which increases the risk of misinterpretation of laboratory results and often overdiagnosis of thyroid dysfunction. On the other hand, thyroid dysfunction is associated with significant risks to pregnancy and the fetus, and the correct assessment of the conditions of hypo- or hyperthyroidism is of paramount importance to prevent complications of pregnancy. The study provides intermediate results of 103 pregnant women from the above groups. All of them had a medical history, a clinical examination and ultrasound examination of the thyroid gland, as well as an assessment of risk factors. Serum concentrations of the following laboratory parameters were measured: thyroid-stimulating hormone (TSH), free thyroxine (FT4), anti-TPO and anti (Tg) antibodies, free triiodothyronone (fT3). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index