| Autor: |
N. ZH., YERIMOVA, B. K., SHIRTAEV, B. B., BAIMAKHANOV, A. T., CHORMANOV, I. Y., SAGATOV, M. M., SUNDETOV, E. A., ENIN, D. R., KURBANOV, K. U., KHALYKOV |
| Předmět: |
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| Zdroj: |
New Armenian Medical Journal; Sep2021, Vol. 15 Issue 3, p84-96, 13p |
| Abstrakt: |
Cytomegalovirus is the most common and significant infection in children after liver transplantation with the development of episodes of CMV infection (CMVI) or CMV disease. CMV infection was first described by M. Ribert in 1881, when cytomegalic cells were found in kidney tissue in congenital syphilis. Cytomegalovirus is widely spread both among patients in a state of long-term drug-induced immunosuppression, and among the General population, according to the R. Razonable study, the incidence of cmvi in the population is from 60 to 100%. About half of children attending preschool institutions have suffered an episode of active cmvi, while this indicator increases by 10-15% every year. N. Singh reports a 27% incidence of cmvi, among 139 patients included in the study, all patients received prophylactic antiviral drugs, a higher (50%) incidence rate was observed in the study of I. Lautenschlager without the use of prevention. A. Jain and co-authors reported a 14.3% incidence of active CMV in patients receiving preventive therapy within a year after transplantation, and E. Gane and co-authors reported a 25% incidence of CMV. During liver transplantation, children should take into account the high risk of developing active cmvi in the postoperative period. Complications of the course of active cmvi are: CMV-a disease with organ damage, CMV-associated rejection of a liver transplant. The Basis of CMV infection prevention should be a combination of monitoring the activity of the infectious process with long-term drug prevention and treatment of all episodes of active CMVI. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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