| Autor: |
Tomihara, Hideo, Hashimoto, Kazuhiko, Ishikawa, Hajime, Terashita, Daisuke, Gakuhara, Atsushi, Fukuda, Shuichi, Ohta, Katsuya, Kitani, Kotaro, Hida, Jin-ichi, Wakasa, Tomoko, Kimura, Yutaka |
| Zdroj: |
Clinical Journal of Gastroenterology; Oct2021, Vol. 14 Issue 5, p1544-1549, 6p |
| Abstrakt: |
Hepatocellular adenoma (HCA) is a rare benign liver tumor that has been reported to occur particularly more often in women who use contraceptives. A 72-year-old woman with no history of using contraceptives presented to our hospital for further examination of a liver tumor. Contrast-enhanced computed tomography and gadoxetic acid-enhanced magnetic resonance imaging revealed a huge solitary hepatic tumor measuring 83 × 76 mm in segments 4, 5, and 8. The differential diagnoses were cholangiocarcinoma and mixed-type hepatocellular carcinoma. Percutaneous needle biopsies were performed twice, and no malignant components were found. Central bi-segmentectomy of the liver was successfully performed. Immunohistochemical staining showed that β-catenin was positive in the membrane of the tumor cells, while fatty acid-binding protein, glutamine synthetase, and amyloid A were negative. These results led to a diagnosis of HCA, hepatocyte nuclear factor-1α-inactivated subtype. The patient's postoperative course was uneventful, and she developed no recurrence for 10 months after surgery. We experienced a rare case of benign HCA. Obtaining a correct preoperative diagnosis is sometimes difficult at the first evaluation. HCA should be considered as a differential diagnosis of liver tumors. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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