| Autor: |
Alaribe, Chinwendum Stephenie, Esposito, Tiziana, Sansone, Francesca, Sunday, Adesegun, Pagano, Imma, Piccinelli, Anna Lisa, Celano, Rita, Cuesta Rubio, Osmany, Coker, Herbert Alexander, Nabavi, Seyed Mohammad, Rastrelli, Luca, Picerno, Patrizia |
| Předmět: |
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| Zdroj: |
Natural Product Research; Sep2021, Vol. 35 Issue 18, p3095-3099, 5p |
| Abstrakt: |
Propolis is an attractive natural ingredient to design health products due to its pharmacological effects. Our chemical investigation of a polar extract of Nigerian propolis (NP) led the isolation and identification of five isoflavonoids (1-4, 6), one diarylpropane (5) and one prenylated flavanone (7) by the combination of chromatographic and spectroscopic techniques. Compounds 1, 4 and 7 were found to be the main markers in NP (8.0, 5.0 and 4.0 mg/g of dry extract, respectively). Moreover, NP and its phenolic constituents exhibited in vitro free radical scavenging activity together with a promising antidiabetic effect against α-amylase and α-glucosidase enzymes. Finally, NP showed also a moderate inhibition of Helicobacter pylori growth. These results suggested that NP could be a good candidate in nutraceuticals and food products. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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