Correlation between dysphonia and dysphagia evolution in amyotrophic lateral sclerosis patients.
| Autor: | Mezzedimi, Chiara, Vinci, Enza, Giannini, Fabio, Cocca, Serena |
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| Předmět: |
PILOT projects
ACADEMIC medical centers NEUROLOGISTS SPEECH disorders MULTIVARIATE analysis PROGRESSIVE bulbar palsy DEGLUTITION disorders DIGESTIVE system endoscopic surgery SPEECH evaluation T-test (Statistics) AMYOTROPHIC lateral sclerosis QUALITY of life HOSPITAL care DESCRIPTIVE statistics VOICE disorders EARLY diagnosis DISEASE risk factors DISEASE complications |
| Zdroj: | Logopedics Phoniatrics Vocology; Oct2021, Vol. 46 Issue 3, p118-125, 8p |
| Abstrakt: | Purpose: Amyotrophic lateral sclerosis (ALS) is a non-demyelinating neurodegenerative disease in adults with motor disorders. It is the most prevalent neuromuscular disease worldwide. Two forms exist: a sporadic form (90% of cases) and a family form due to mutations in more than 20 genes. Patient clinical characteristics are muscle weakness, dysphagia, dysphonia and respiratory failure. The cause of ALS is unknown as we do not know why it affects some people and not others. The aim of this pilot study is to evaluate the possible relationship between dysphonia and dysphagia in ALS patients and if a deterioration of speech ability is linked with a worsening of dysphagia. Between March 2017 and February 2018, 27 newly diagnoses patients (about 2 months) were examined in the ENT Clinic of our University Hospital. The bulbar-onset of ALS was diagnosed by neurologists. According to the endoscopic and clinical results, patients were classified in 4 classes of dysphagia. Laryngology and speech pathology assessment with spectroacuostic analysis of speech using Praat software are fundamental for the proper evaluation of dysphonia of these patients. This study was the first attempt to find a vocal indicator of advancement in swallowing dysfunction in the patient population of ALS. Preliminary findings indicate that the reduction in the maximum fundamental frequency is associated with advancement of dysphagia. Monitoring the vocal parameters could be useful in order to give an early rehabilitation aid to these patients improving their quality of life and reducing aspiration risks. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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