CYTOKINES PROFILE FOR INTESTINAL AND SPLEEN HOMOGENATE FOR IMMUNOSUPPRESSANT BALB/C MICE INFECTED WITH CRYPTOSPORIDIUM PARVUM.

Autor: Hasan, Thikra F., AL-Abassi, Hazima M., Ali, Hayder Zuhair
Předmět:
Zdroj: Biochemical & Cellular Archives; 2021Supplement1, Vol. 21, p2215-2221, 7p
Abstrakt: Cryptosporidiosis is mainly cause a persistent diarrhea in immune compromised patients, BALB/c mice have been suppressed by dexamethasone, tissue Th1, Th2 and Th17 cytokines concentrations in the ileum were significantly diminished in both infected and immunosuppressed mice. Level of IFN-γ, TNF-α, IL-12, IL-6, IL-17A was increased in level, IL-4 didn’t increases, in both ileal and spleen tissue. Levels of above cytokines were examined in spleen in order to follow the proliferation of CD4+ T-cell during C. parvum infection. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index