Clerodane-type Diterpene Glycosides from Dicranopteris pedata.

Autor: Gao, Bei-Bei, Ou, Yu-Fei, Zhu, Qin-Feng, Zhou, Zhi-Ping, Deng, Zhen-Tao, Li, Meng, Zhao, Qin-Shi
Předmět:
Zdroj: Natural Products & Bioprospecting; Oct2021, Vol. 11 Issue 5, p557-564, 8p
Abstrakt: Three new clerodane-type diterpene glycosides, (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene (1), (5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-2-ox-oneocleroda-3,13-dien-15-ol (2), (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-(13E)-2-oxoneocleroda-3,14-dien-13-ol (3), together with two known compounds 4 and 5 were isolated from Dicranopteris pedata. The structures of these compounds were elucidated by detailed spectroscopic analysis, and the absolute configuration of compound 2 was determined by ECD calculations. In addition, compound 1 exhibited weak inhibitory activities against SMMC-7721, MCF-7 and SW480. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index