| Autor: |
Juping Wang, Rongxing Xiao, Kangcheng Zheng, Li Qian |
| Předmět: |
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| Zdroj: |
Dalton Transactions: An International Journal of Inorganic Chemistry; 9/7/2021, Vol. 50 Issue 33, p11370-11375, 6p |
| Abstrakt: |
The mechanism and site-selectivity for Fe-catalyzed azaindoline formation from 1,2,3,4-tetrazole were examined computationally. The H-atom abstraction/radical rebound stepwise mechanism is proposed. The aliphatic H-atom abstraction (HAA) vs. electrophilic aromatic substitution (EAS) steps are responsible for the sp³ vs. sp² C-H amination site-selectivity and a larger steric congestion disfavors sp² EAS, thus resulting in Fe-catalyzed site-selectivity toward sp³ C-H amination. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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