| Autor: |
Olivia, Niken, Kusumadewi, Wiwin-winda, Sumito, Nandini, Murdiastuti, Kwartarini |
| Předmět: |
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| Zdroj: |
Indian Journal of Public Health Research & Development; Jul-Sep2021, Vol. 12 Issue 3, p446-453, 8p |
| Abstrakt: |
Background: Platelet-rich plasma (PRP) which is made by blood donors (homologous) from the blood bank (Palang Merah Indonesia), is named homologous PRP (HPRP) that can be used for periodontal tissue regeneration therapy.The freeze-drying and a terminal sterilization processes have to be done so that h-PRP haslengthen store time, maintained the level of growth factors comparable to fresh PRP and also to stop retroviruses activity. The both procedures can influence the cells and stimulates growth factor release from the platelets and granulocytes. The effectiveness of growth factors in FD HPRP can enhance the migration of osteoblasts, which are involved in the healing of periodontal tissues.The research aim was to investigate the effect of FD HPRP into the migration of osteoblast. Methods: The HPRP was freeze-dried and done γ-irradiation by 20 and 25 KGy for the sterilization and and compared with Injectable Platelet-Rich Fibrin (iPRF) (positive control group) and one group non treated as negative control so that there were 4 group experiments. The migration of osteoblasts were measured after 24 hours and the data were analyzed by one way ANOVA test. Result: There were not significant differences among FD HPRP 20, FD HPRP 25 and iPRF(p >0.05) but significant differences with negative control (p<0.05). Conclusion: There was effect among of FD HPRP20 and 25 on osteoblast migration. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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