Antifungal and phytotoxic activity of benzoic acid derivatives from inflorescences of Piper cumanense.

Autor: Parra Amin, Jorge Emilio, Cuca, Luis E., González-Coloma, Azucena
Předmět:
Zdroj: Natural Product Research; Aug2021, Vol. 35 Issue 16, p2763-2771, 9p
Abstrakt: The Piperaceae family is recognized for its diverse biological properties such as antifungal, antibacterial, cytotoxic and insecticidal activities. Phytochemical investigation of inflorescences from P. cumanense led to the isolation and identification of a new 4-chromanone called oxocumanensic acid, along with five known benzoic acid derivatives. The antifungal activity was evaluated against six phytopathogenic fungi by a mycelium growth inhibition test. All compounds were active against the phytopathogenic fungi, showing a greater activity against fungi of Fusarium genus. Finally, phytotoxicity was evaluated in the extract and its chemical constituents, finding that the natural substances are less toxic than the positive control. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index