| Autor: |
HIDEYUKI HONGO, KOICHI TOKUUE, TAKEJI SAKAE, MISATO MASE, MOTOKO OMURA |
| Předmět: |
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| Zdroj: |
In Vivo; Sep/Oct2021, Vol. 35 Issue 5, p2655-2659, 5p |
| Abstrakt: |
Background/Aim: To evaluate the robustness of radiotherapy treatment planning optimization for respiratorymoving breast cancer using fixed-angle beams planning TomoDirect™ intensity-modulated radiotherapy (IMRT). Materials and Methods: A minimax optimisation algorithm was applied to 10 breast cancer patients. Two sets of treatment plans with or without robust techniques were prepared considering anterior-posterior and head-tail movements due to respiration. Parameters were compared between treatment plans: 95% planned target volume (PTV) dose, conformal index and homogeneity index (HI), and organs at risk (OAR) parameters including the lung volume receiving 20 Gy or more (V20) and 5 Gy (V5). Results: Robust planning significantly improved parameters of 95% PTV dose and HI, without deteriorating V20 or V5 in the anterior-posterior movement, while it slightly improved 95% PTV and slightly deteriorated V20 in the head-tail movement. Conclusion: Robust treatment planning improves coverage of targets moving because of respiration in the treatment of breast cancer using TomoDirect; however, normal lung doses should be cautiously evaluated on a case-by-case basis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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