Photoelectrochemical Sensor for Isoniazid: Application in Drugs Used in the Treatment of Tuberculosis.

Autor: Nascimento Botelho, Chirlene, Pavão e Pavão, Daniele, Santos Damos, Flávio, de Cássia Silva Luz, Rita
Předmět:
Zdroj: Electroanalysis; Aug2021, Vol. 33 Issue 8, p1936-1944, 9p
Abstrakt: The present work describes the development of a photoelectrochemical sensor based on titanium dioxide, cadmium telluride quantum dots and the tris (2,2′‐bipyridyl) ruthenium(II) chloride complex for detection of Isoniazid (INH). The Ru(bpy)32+/CdTe‐QDs/TiO2/FTO photoelectrochemical platform was characterized by scanning electrochemical microscopy, electrochemical impedance spectroscopy and amperometry. The photoelectrochemical sensor presented two linear ranges for INH concentrations ranging from 0.5 to 150 μmol L−1 and 150 to 1270 μmol L−1, with a theoretical detection limit of 0.02 μmol L−1. The sensor was successfully applied for the determination of INH in drugs samples used in the treatment of tuberculosis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index