| Autor: |
AL-Nasrawi, Abd Ali, Adil Ateyah, Aljarah, Ali Kadhim, Muhammed, Hayder Ali |
| Předmět: |
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| Zdroj: |
Indian Journal of Forensic Medicine & Toxicology; Jul-Sep2021, Vol. 15 Issue 3, p4904-4915, 12p |
| Abstrakt: |
Both Periodontitis & Atherosclerosis of Cardiovascular system are chronic inflammatory disorders can be performed by invasion of their connective tissues with aerobic & anaerobic infectious bacteria & formation of polymicrobial biofilms. Microbial & metabolic plaques are considered to be the initiating factor for many infectious & metabolic diseases, invasion of an oral & systemic organs with various opportunistic pathogens have been reported in many populations. Several studies have been published Conventional & Real time PCR with 16S r RNA gene to improve the existence of the DNA molecules of the most invasive periodontics pathogens in atheromatous plaques of diabetic & cardiovascular blood vessels disease patients. In the present study, among 100 atherosclerotic & diabetic patients suffered from various degrees of ischemic heart disease, the DNA molecules of Treponema denticola was detected in (45/100)45% of atheromatous plaque samples significantly in male 28 /45 (62%) more than 17/45(38%) in female patients (p = 0.07) with no significant importance in cardiovascular & diabetic patients more than 50 years old 23/45(51%) which was approximate to 22/45(49%) in younger than 50 years old. As well as, T. denticola DNA molecules were significantly displayed in atheromatous plaques of type (1, 2) diabetic patients 35 /45 (78%) more than in non-diabetic group 10/45(22%) (p= 0.07) & T. denticola DNA molecules did not displayed in the controller group. In conclusion: the present cross sectional study demonstrated the invasion of atheromatous plaques of cardiovascular atherosclerotic vessels & diabetic patients with highly aggressive anaerobic periodontal spirochetes T. denticola, these results improve the existence of additional risk factor that interfere with the pathogenesis of periodontitis & genesis of cardiovascular atherosclerosis & may be correlated with the atherosclerosis & diabetes mellitus diseases patients in Iraqi population. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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