Leprosy and AIDS: two cases of increasing inflammatory reactions at the start of highly active antiretroviral therapy.

Autor:	Pignataro, P., da Silva Rocha, A., Nery, J. A. C., Miranda, A., Sales, A. M., Ferrreira, H., Valentim, V., Suffys, P. N.
Předmět:	HANSEN'S disease AIDS ANTIRETROVIRAL agents MYCOBACTERIUM leprae POLYMERASE chain reaction MYCOBACTERIUM avium
Zdroj:	European Journal of Clinical Microbiology & Infectious Diseases; May2004, Vol. 23 Issue 5, p408-411, 4p
Abstrakt:	Reported here are the cases of two HIV-positive patients with skin lesions suggestive of leprosy, based on clinical and pathological analysis, which worsened during the few weeks following initiation of highly active antiretroviral therapy. The lesions improved after a few weeks of multidrug therapy for leprosy. Mycobacterium lepra was confirmed by polymerase chain reaction analysis of blood in case 1 and of a biopsy sample in case 2. Neither Mycobacterium avium complex nucleic acid, which is usually associated with immune restoration syndrome, nor mycobacterial cutaneous manifestations were detected in either case. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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