| Autor: |
Akulov, Mikhail A., Tanyashin, Sergey V., Usachev, Dmitriy Y., Shimanskiy, Vadim N., Orlova, Olga R., Zakharov, Vladimir O., Karnaukhov, Vasiliy V., Kolycheva, Mariya V., Khatkova, Svetlana E., Bolevich, Sergej B., Orlova, Aleksandra S. |
| Předmět: |
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| Zdroj: |
Serbian Journal of Experimental & Clinical Research; Jun2021, Vol. 22 Issue 2, p137-144, 8p |
| Abstrakt: |
Introduction: Delayed facial palsy (DFP) is a common complication appearing ≥3 days after neurosurgery. In cases where glucocorticoids are contraindicated, other treatments are needed. Methods: The efficacy of BoNT-A injections was evaluated in patients with DFP after vestibular schwannoma resection. Patients received: Group I, BoNT-A (40–50 IU); Group II, prednisolone (1 mg/kg per day, 5–7 days); Group III, glucocorticoids with BoNT-A; Group IV, refused treatment. Functional efficacy was assessed. Results: Among 75 patients, pretreatment facial nerve dysfunction was mild, moderate, and moderate-to-severe in 48.0%, 33.3%, and 18.7%, respectively. One month post-treatment initiation, Group III had a significantly higher rate of facial symmetry normalization versus Groups II and IV (P < 0.05). After 3 months, complete recovery of facial nerve function was significantly higher in Groups I–III versus Group IV (P < 0.05). Conclusion: BoNT-A injections may be recommended for DFP treatment to attenuate facial asymmetry and improve functional recovery. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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