Metastatic Ewing's Sarcoma of the Adrenal Gland in a Young Indian Male: a Rare Fate.

Autor:	Talwar, Harkirat Singh, Mittal, Ankur, Panwar, V. K., Narain, T. A.
Předmět:	THERAPEUTIC use of antineoplastic agents ETOPOSIDE IMMUNOHISTOCHEMISTRY DOXORUBICIN METASTASIS IFOSFAMIDE TREATMENT effectiveness CYCLOPHOSPHAMIDE TEMOZOLOMIDE ADRENAL tumors EWING'S sarcoma RARE diseases NEEDLE biopsy VINCRISTINE
Zdroj:	Indian Journal of Surgery; Jun2021, Vol. 83 Issue 3, p767-769, 3p
Abstrakt:	Ewing's sarcoma of the adrenal gland is rare, and only a few cases have been reported in literature so far. We report a case of a young male with a large mass in the left suprarenal region with infiltration into the surrounding organs and multiple osteoblastic skeletal metastases. Biopsy and immunohistochemistry were consistent with a diagnosis of Ewing's sarcoma. He was started on vincristine, adriamycin, and cyclophosphamide alternating with ifosfamide and etoposide (VAC/IE) chemotherapy. A post chemotherapy scan showed a progressive disease, and an alternative regimen of vincristine, irinotecan, and temozolomide was started. He could receive only one cycle before he succumbed to his illness. This case underlines the natural course of disease in patients with de novo metastatic Ewing's sarcoma, and although the treatment of metastatic Ewing's is not standardized, this case highlights the best treatment strategies for patients with such poor prognosis so as to preserve valuable resources and provide maximal survival benefit. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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