Effectiveness and Safety of a Single-Dose Ivermectin Treatment for Uncomplicated Strongyloidiasis in Immunosuppressed Patients (ImmunoStrong Study): The Study Protocol.

Autor: Salvador, Fernando, Lucas-Dato, Ana, Roure, Silvia, Arsuaga, Marta, Pérez-Jacoiste, Asunción, García-Rodríguez, Magdalena, Pérez-Molina, José A., Buonfrate, Dora, Saugar, José María, Molina, Israel
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Zdroj: Pathogens; Jul2021, Vol. 10 Issue 7, p812-812, 1p
Abstrakt: Strongyloidiasis affects an estimated 600 million people worldwide, especially in tropical and subtropical areas. Single-dose ivermectin treatment has shown to be effective among immunocompetent patients with uncomplicated strongyloidiasis. Here, we present the protocol of the ImmunoStrong study, a prospective observational study aiming to evaluate the effectiveness and safety of a single-dose ivermectin for treatment of uncomplicated strongyloidiasis in immunosuppressed patients. The secondary objectives are to assess accuracy of molecular techniques for the follow-up of these patients and to determine the population pharmacokinetics of ivermectin. The information retrieved by this study will cover relevant information gaps in the strongyloidiasis management among immunosuppressed patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index