| Autor: |
Sultana, Afrin, Nobi, Farah, Arefin, Mirza Shamsul, Hossain, Tasmina, Hossain, Mehran |
| Předmět: |
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| Zdroj: |
Indian Journal of Basic & Applied Medical Research; Jun2021, Vol. 10 Issue 3, p53-64, 12p |
| Abstrakt: |
Background: The goal of breast conservation surgery is to completely remove the identified cancer while preserving adequate breast tissue to achieve an acceptable cosmetic result. Objectives: To evaluate the effectiveness of wide local excision with 1cm resection margin with axillary sampling or dissection for early breast cancer without frozen section facility. Methods: This was a prospective histopathological study designed to evaluate the resection margins among wide local excision (WLE) specimens with early breast cancer treated by mastectomy with axillary dissection up to level 2. Fifty female patients with stage 1&2 Breast Cancer were selected by purposive sampling. Lumpectomy specimen was oriented & marked for margins and sent for histopathology to assess the resection margin status. Results: Maximum women 58.0% were postmenopausal. 68.0% had upper outer quadrant followed by lower outer quadrant 16.0%. Clinical TNM staging were observed maximum 50.0% T2N0 followed by 32% were T2N1. Resection margin was positive in 3 cases, 2 positive in lateral margin and 1 in medial margin. FNAC findings of the breast carcinoma patients, maximum (70.0%) patients had ductal cell carcinoma (DCC). Most common histopathological findings were invasive duct cell carcinoma 45(90.0%). Pathological TNM staging were observed maximum 38.0%. Among 3 cases who had positive 1 cm resection margin, 1(33.3%) patients had TNM staging (pathological) T2N1, 1(33.3%) T1N2 and 1(33.3%) patient had T2N3. A p value was <0.05, that was statistically significant. Conclusion: Lumpectomy with 1 cm resection margin is a standard surgical procedure in the management of early stage breast cancer. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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