Dose–response association between adult height and all-cause mortality: a systematic review and meta-analysis of cohort studies.

Autor: Li, Quanman, Liu, Yu, Sun, Xizhuo, Li, Honghui, Cheng, Cheng, Liu, Leilei, Liu, Feiyan, Zhou, Qionggui, Guo, Chunmei, Tian, Gang, Qie, Ranran, Han, Minghui, Huang, Shengbing, Li, Linlin, Wang, Bingyuan, Zhao, Yang, Ren, Yongcheng, Zhang, Ming, Hu, Dongsheng, Wu, Jian
Předmět:
Zdroj: European Journal of Public Health; Jun2021, Vol. 31 Issue 3, p652-658, 7p
Abstrakt: Background We conducted a systematic review and meta-analysis from published cohort studies to examine the association of adult height and all-cause mortality and to further explore the dose–response association. Methods PubMed, The Cochrane Library, The Ovid, CNKI, CQVIP and Wanfang databases were searched for articles published from database inception to 6 February 2018. We used the DerSimonian–Laird random-effects model to estimate the quantitative association between adult height and all-cause mortality and the restricted cubic splines to model the dose–response association. Results We included 15 articles, with 1 533 438 death events and 2 854 543 study participants. For each 5-cm height increase below the average, the risk of all-cause mortality was reduced by 7% [relative risk (RR) = 0.93, 95% confidence interval (CI), 0.89–0.97] for men and 5% (RR = 0.95, 95% CI, 0.90–0.99) for women. All-cause mortality had a U-shaped association with adult height, the lowest risk occurring at 174 cm for men and 158 cm for women (both P nonlinearity < 0.001). Relative to the shortest adult height (147 cm for men and 137 cm for women), men at 174 cm had a 47% lower likelihood of all-cause mortality and women at 158 cm a 33% lower risk of all-cause mortality. Conclusions Our study suggests that the relation between adult height and all-cause mortality is approximately U-shaped in both men and women. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index