| Autor: |
MACKE, CHRISTIAN, LENHOF, STEFAN, GRAULICH, TILMAN, ÖRGEL, MARCUS, OMAR-PACHA, TAREK, STÜBIG, TIMO, KRETTEK, CHRISTIAN, OMAR, MOHAMED |
| Předmět: |
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| Zdroj: |
In Vivo; Jul/Aug2021, Vol. 35 Issue 4, p2409-2416, 8p |
| Abstrakt: |
Background/Aim: We aimed to determine the diagnostic value of the synovial aspiration culture prior to reimplantation in two- (or more) stage exchange of periprosthetic joint infection. Patients and Methods: This was a retrospective study, spanning over ten years including all synovial cultures of patients with two- (or more) stage exchange due to periprosthetic joint infection. Results: A total of 183 patients were included, mean age was 66.6 years (range=12.8-93.4 years). Overall sensitivity of synovial aspiration cultures before reimplantation was 56.6%, specificity 84.6%, negative predictive value (NPV) 63.8%, positive predictive value (PPV) 80.2%, area under the curve (AUC) 70.6%. Sensitivity of the knee in comparison to the hip culture was significantly higher, as well as the NPV and the AUC (p=0.038). In case of complete removal of prosthesis, the sensitivity and AUC were significantly reduced, whereas the specificity was comparable with prosthesis in situ, partial removal or complete removal. Conclusion: Due to the low sensitivity, obtaining several synovial cultures in the prosthesis-free interval to exclude persistence of infection, does not seem reasonable. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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