| Autor: |
Li, Xiangli, He, Yiming, Yang, Lin, He, Zhimei, Zhu, Jun-Jie |
| Předmět: |
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| Zdroj: |
Chemical Communications; 7/14/2021, Vol. 57 Issue 55, p6776-6779, 4p |
| Abstrakt: |
We report the straightforward synthesis of ATP-responsive nanoscale metal azolate framework-7 (MAF-7) for gene/drug codelivery. The MAF-7 functions as (i) the armour to preserve DNAzymes, (ii) an ATP scavenger to lower the intracellular ATP level, and (iii) a built-in Zn2+ arsenal to initiate the biocatalysis of DNAzymes, ultimately inhibiting P-gp expression to enhance chemotherapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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