| Autor: |
Yue, Guizhou, Jiang, Dan, Dou, Zhengjie, Li, Sicheng, Feng, Juhua, Zhang, Li, Chen, Huabao, Yang, Chunping, Yin, Zhongqiong, Song, Xu, Liang, Xiaoxia, Wang, Xianxiang, Lu, Cuifen |
| Předmět: |
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| Zdroj: |
New Journal of Chemistry; 7/14/2021, Vol. 45 Issue 26, p11712-11718, 7p |
| Abstrakt: |
The umpolung Michael addition of isatin N,N′-cyclic azomethine imine 1,3-dipoles with chalcones is reported. The reaction could be finished within a very short time (0.3–2 min), with 3,3-disubstituted oxindole derivatives obtained in moderate to excellent yields with promising dr values. Unusual Michael adducts were obtained in moderate to high yields (26–98%) with low to high diastereoselectivities (0.8 : 1 to 8.5 : 1 dr). All the synthesized compounds (3, 3′, 4, 5, 5′, 7, 7′, 9 and 9′) were well characterized by FTIR, NMR, and mass spectral analyses and further confirmed by the single-crystal X-ray diffraction analysis of compounds 3aa and 4n. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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