Iron Status and Neurobehavioral Development of Premature Infants.

Autor: Armony-Sivan, Rinat, Eidelman, Arthur I., Lanir, Amos, Sredni, Devora, Yehuda, Shlomo
Předmět:
Zdroj: Journal of Perinatology; Dec2004, Vol. 24 Issue 12, p757-762, 6p
Abstrakt: OBJECTIVE:: This study was conducted to examine the relation between iron status and neurobehavioral development in premature infants. STUDY DESIGN:: Infants born before 34 weeks postmenstrual age and who were medically stable were studied. Anemia was defined as hemoglobin=10?g/Dl and low iron stores as a serum ferritin concentration=75?µg/l. The infants were classified as anemic with low ferritin (Group 1; n=18), anemic with normal ferritin (Group 2; n=14), and nonanemic with normal ferritin (Group 3; n=21). A total of 18 reflexes were behaviorally evaluated at 37 weeks postmenstrual age and“reflex scores”were compared between the groups. Higher scores reflect a greater percentage of abnormal reflexes. RESULTS:: Infants in group 1 (anemia/low ferritin) had a significantly higher reflex score (51.45±18.32%) than infants in Group 3 (38.32±17.75%). Group 2 had an intermediate score (45.40±21.70%), but not different from the other two groups. CONCLUSION:: These data indicate that low iron status, both measured by anemia and ferritin levels, is related to poorer neurobehavioral status in premature infants.Journal of Perinatology (2004) 24, 757-762. doi:10.1038/sj.jp.7211178 Published online 19 August 2004 [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index