| Autor: |
Nassrallah, Basheer, Bamberger, Ellen, Cohen, Sarah, Srugo, Isaac, Golan-Shany, Orit, Shlonsky, Yulia, Mubariki, Raeda, Genizi, Jacob |
| Předmět: |
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| Zdroj: |
European Journal of Clinical Microbiology & Infectious Diseases; Jul2021, Vol. 40 Issue 7, p1553-1557, 5p |
| Abstrakt: |
We retrospectively examined the yield of a cerebrospinal fluid (CSF) multiplex real-time PCR assay of febrile young infants undergoing a full sepsis work-up. Eighty infants were included in the study: Forty-nine (61%) neonates and 31 (39%) 29–90 day-old patients were included in the study. A viral pathogen was detected in 59% (47/80) of the samples, human enterovirus in 53% (42/80) and Human parechovirus in 6% (5/80). The CSF of nearly half of the subjects with CNS infection was without pleocytosis; all CSF cultures were negative. Multiplex PCR CSF testing enhances the diagnosis of pathogen-specific viral CNS infection among febrile young infants. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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