| Autor: |
Sadaria, Roshni G., Vasava, Smita N. |
| Předmět: |
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| Zdroj: |
Indian Journal of Forensic Medicine & Toxicology; Apr-Jun2021, Vol. 15 Issue 2, p681-685, 5p |
| Abstrakt: |
Background: Chronic kidney disease (CKD) is defined as abnormalities in kidney structure or function present for > 3 months and have other health implications. Thyroid hormones are important for electrolyte homeostasis and also for the growth and development of the kidney. Study shows that hypothyroidism is commonly seen in later stages of CKD. This study was conducted to investigate thyroid hormone profile and its correlation with creatinine in CKD patients. Materials and Methods: The present case control study was conducted at Dhiraj General Hospital, Piparia, Vadodara, Gujarat, India in which 100 subjects were enrolled, out of which 50 were cases of CKD patients and 50 were controls. The age group for the study was 18 to 70 years. Blood samples were drawn to measure blood urea, serum creatinine, thyroid profile. Interpretation of data was done using Medcalc software. Conclusion: Serum TSH levels were high in cases compared to controls but results were not significant. Significant negative correlation was found between free thyroid hormones and serum creatinine. Correlation of creatinine with T3, T4 and TSH were not significant. Subclinical hypothyroidism is found in our population with undialyzed CKD. More studies involving large population size are required to ascertain these findings. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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