Sirtuin as Molecular Regulator, Gerontology Tool: A Review of Sirtuin System, Characterization and Function in Molecular Biology.

Autor: REVATHI N., ARJUNANA, NIVETHA C., GOWRI A., VIJAYAKUMAR T., SIVA, MUTHUSELVAM M.
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Zdroj: International Journal of Pharmaceutical Research (09752366); Jul-Sep2021, Vol. 13 Issue 3, p273-280, 8p
Abstrakt: The single gene that correlates with many genetic diseases and disorders, as well as ageing and age-related diseases, is the subject of this research. SIRT1 is a gene that plays a role in the ageing process and age-related disorders including early ageing, vision, Alzheimer's disease, dementia, cancer, skin problems, and so on. The extraordinary and significant capacity of the quality is to upgrade the telomerase action. Telomerase is the protein that shields the finish of the chromosomes from the harm. Telomerase goes about as defensive container layer that forestalls the chromosomes. The shortening of telomerase prompts the way toward maturing. Many exploration shows that the polyphenolic compound particularly resveratrol from grapes shows dynamic outcome in the incitement of sirtuins quality and studies shows that the cycle lead expansion of life expectancy. The examination on the specific quality shws that it includes in different exercises like cell cycle, apoptosis, disease, Neurodegenerative problems and so forth, The point of the investigation centering towards the significant exploration work on the sirtuins quality and its capacities in different measurements. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index