Copper-Catalyzed Synthesis of β- and δ-Carbolines by Double N-Arylation of Primary Amines.

Autor: Van Phuc, Ban, Do, Ha Nam, Quan, Nguyen Minh, Tuan, Nguyen Ngoc, An, Nguyen Quang, Van Tuyen, Nguyen, Anh, Hoang Le Tuan, Hung, Tran Quang, Dang, Tuan Thanh, Langer, Peter
Předmět:
Zdroj: Synlett; 2021, Vol. 32 Issue 10, p1004-1008, 5p
Abstrakt: Two efficient and practical approaches are reported for the synthesis of β- and δ-carbolines from 3,4-dibromopyridine. The synthesis is based on site-selective Cu-catalyzed double C–N coupling reactions and subsequent annulations by twofold Pd-catalyzed C–N coupling with amines. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index