| Autor: |
Lucyshyn, Danica R., Knickelbein, Kelly E., Hollingsworth, Steven R., Reilly, Christopher M., Brust, Kelsey D., Visser, Lance C., Burge, Rhonda, Willcox, Jennifer L., Maggs, David J. |
| Předmět: |
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| Zdroj: |
Veterinary Ophthalmology; May2021, Vol. 24 Issue 3, p301-307, 7p |
| Abstrakt: |
Objective: To report onset and progression of clinical signs of a neuroendocrine neoplasm (NEN) presumed metastatic to the choroid in a dog. Animals Studied: A 7.5‐year‐old female spayed German shepherd dog mix referred for advanced imaging and evaluation of a subretinal mass in the right eye. Procedures: Procedures performed included general physical and ophthalmic examinations; ocular, orbital, and abdominal ultrasonography; thoracic radiographs; cranial magnetic resonance imaging; serologic testing for infectious agents; analysis of hematologic as well as serum and urine biochemical parameters; echocardiography; electrocardiography; cytologic assessment of lymph nodes; and histopathology and immunohistochemistry of the enucleated globe. Results: Examination and imaging identified a pigmented mass within and expanding the superior choroid. Following enucleation, a choroidal NEN with tumor emboli in scleral blood vessels was diagnosed by histopathologic assessment and confirmed by immunohistochemical labelling. Despite extensive and repeated diagnostic testing over many months, a putative primary site was not identified until 19 months after the initial ocular signs were noted. At that time, a heart‐base mass and congestive heart failure were highly suggestive of a chemodectoma. Conclusion: This comprehensive report of a NEN presumed metastatic to the choroid in a dog suggests that ocular disease can be a very early and solitary sign of NEN in the dog. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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