| Autor: |
Yassine, Hasna, Bouali, Jamila, Oumessaoud, Asmaa, Ourhzif, El Mahdi, Hamri, Salha, Hafid, Abderrafia, Khouili, Mostafa, Pujol, Maria Dolors |
| Předmět: |
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| Zdroj: |
Synthesis; 2021, Vol. 53 Issue 11, p1971-1979, 9p |
| Abstrakt: |
The 2-(alkylcarbonyl)benzoic acids obtained by esterification of phthalic anhydride are converted into azide derivatives: alkyl 2-[(azidocarbonyl)amino]benzoates and to ureas: dialkyl 2,2′-[carbonyl bis (azanediyl)]dibenzoates. These transformations were carried out using classical Curtius rearrangement conditions in the presence of diphenylphosphoryl azide (DPPA) in a basic medium, followed by hydrolysis. Subsequently, a final condensation reaction of these urea derivatives enabled us to obtain, for the first time, the new alkyl derivatives, alkyl 2-[2,4-dioxo-1,2-dihydroquinazolin-3(4 H)-yl]benzoates. All the new compounds obtained in satisfactory yields were characterized by1 H and13 C NMR, and by X-ray crystallographic analysis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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