| Autor: |
Bueno e Silva, Ana Carolina, Márcia Anchieta, Leni, Rosado, Viviane, Ferreira, Janita, Trindade Clemente, Wanessa, Sampaio Coelho, Julia, Orlandi Mourão, Paulo Henrique, de Castro Romanelli, Roberta Maia |
| Předmět: |
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| Zdroj: |
Jornal de Pediatria; May/Jun2021, Vol. 97 Issue 3, p329-334, 6p |
| Abstrakt: |
Objective: The use of broad-spectrum antimicrobials, such as third and fourth-generation, are responsible for emergence of multidrug-resistant microorganisms in neonatal units. Furthermore, antimicrobial daily doses are not standardized in neonatology. This study aimed to investigate the association between the use of antimicrobial broad spectrum to bacterial sensitivity profile in a referral unit of neonatal progressive care. Methods: This is a cohort study conducted in a referral neonatal progressive care unit from January 2008 to December 2016. The data of all hospitalized neonates was collected daily. The infection criteria used were the standardized national criteria, based on definitions of Center for Diseases Control and Prevention. In this study, the use of antimicrobials was evaluated as antimicrobial-day (ATM-day) and the ratio of multidrug-resistant microorganisms per 1000 ATMday of broad spectrum was also calculated. The study was approved by the Institutional Review Board of the Universidade Federal de Minas Gerais (ETIC 312/08 e CAAE 58973616.2.0000.5149). Results: From 2008 to 2016, 2751 neonates were hospitalized, corresponding to 60,656 patientdays. The ratio of multidrug-resistant microorganisms per 1000 ATM-day of broad spectrum was 1,3 in the first period and 4,3 in the second period (p = 0,005). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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