Friedländer Synthesis of Novel Polycyclic Quinolines Using Solid SiO2/H2SO4 Catalyst.

Autor: Satheeshkumar, Rajendran, Shanmugaraj, Krishnamoorthy, Delgado, Thalia, Bertrand, Jeanluc, Brito, Iván, Salas, Cristian O.
Předmět:
Zdroj: Organic Preparations & Procedures International; 2021, Vol. 53 Issue 2, p138-144, 7p
Abstrakt: (C19H14FNO [M + H]+: Found: 352.033 Calcd.: 352.236)
7.5a295C19H15NO152-154 (151-15319)1693, 15582.193-2.258 (m, 2H, C3-CH2), 2.662-2.695 (m, 2H, C4-CH2), 3.337-3.368 (m, 2H, C2-CH2), 7.139-7.163 (m, 2H, C9-, C13-H), 7.351-7.392 (m, 1H, C17- H), 7.424-7.488 (m, 4H, C10-, C11-, C12-, C16- H), 7.713-7.755 (m, 1H, C15-H), 8.040 (d, 1H, C18-H, J = 8.4 Hz)21.40, 34.62, 40.66, 123.90, 126.45, 127.57, 128.05, 128.13, 128.26, 128.50, 131.76, 137.67, 148.69, 151.50, 162.27, 197.98Calcd.: C, 83.49; H, 5.53; N, 5.12; Found C, 83.41; H, 5.61; N, 5.04. Found: C, 66.63; H, 3.89; N, 4.15.
10.5d2.590C19H14N2O3188-190 (186-18820)1694; 15522.227-2.292 (m, 2H, C3-CH2), 2.704-2.737 (m, 2H, C4-CH2), 3.374-3.406 (m, 2H, C2-CH2), 7.147- 7.174 (m, 2H, C10, C12-H), 7.509-7.535 (m, 3H, C9, C11, C13-H), 8.151 (d, 1H, J = 9.20 Hz, C18-H), 8.390 (d, 1H, J = 2.40 Hz, C15-H), 8.475 (dd, 1H, Jm= 2.40 Hz, Jo= 9.20 Hz, C17-H)21.03, 34.85, 40.47, 124.91, 125.05, 125.33, 126.81, 128.05, 128.57, 130.59, 135.81, 145.58, 150.48, 153.25, 166.14, 197.10.Calcd.: C, 71.69; H, 4.43; N, 8.80. [Extracted from the article]
Databáze: Complementary Index