| Autor: |
Sil, Koelina, Roy, Sudipta, Ray, Jayanti, Mandal, Lopamudra |
| Předmět: |
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| Zdroj: |
Indian Journal of Basic & Applied Medical Research; Mar2021, Vol. 10 Issue 2, p53-59, 7p |
| Abstrakt: |
Introduction: Dengue fever is an important arboviral disease with significant impact of the disease burden specially in tropical countries. The virus seems to have some hepatotoxic and other gastrointestinal effects. Although asymptomatic in most cases, clinical manifestations like jaundice, and acute liver failure (ALF), acute pancreatitis may occasionally complicate the clinical scenario. Our present study focuses on the hepatic and pancreatic manifestations in dengue. Materials and methods:- About hundred patients with acute febrile illness diagnosed to have dengue fever as per WHO criteria were included in our study. Observation: - About 54 patients were males and 46 were females. Their age varied from 13 to 70 years with maximum incidence occurred in 21-30 years age range. Most of the cases presented with various gastro hepatic manifestations. The commonest gastrointestinal manifestation was transaminitis (96%) (Both symptomatic and asymptomatic) followed by hypoprotinaemia, elevated PT (INR),and acute pancreatitis (18%). Pain abdomen(33%) and vomiting(31%) were the common clinical presentations followed by jaundice, pallor, hepatosplenomegaly, GI bleeding, altered sensorium etc,. About 18% of patients presented with acute pancreatitis as per Revised Atlanta classification criteria. Conclusion: Liver and pancreatic injury is very common in patients with Dengue fever. Severity of hepatic and pancreatic involvement can be a major contributing factor in morbidity and mortality in patients with Dengue . These various atypical manifestations should prompt us to investigate for dengue so that expanded dengue syndrome can be diagnosed and treated early. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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