Prospective Evaluation of the Impact of Gastroenterological Manifestations on Length of Stay and Survival in Critically III COVID-19 Patients in Mississippi.

Autor: OWINGS, ANNA H., SLOAN, MEREDITH E., SIVA, SHIVI, SENITKO, MICHAL, ABRAHAM, GEORGE, ROBINSON, TANYA O., PRIDE, YILIANYS, LAIRD, HANNAH, PARKER, ADAM, WILSON, KEN J., HILLEGASS, WILLIAM B., GLOVER, SARAH C.
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Zdroj: Journal of the Mississippi State Medical Association; Nov/Dec2020, Vol. 61 Issue 11, p400-403, 4p
Abstrakt: SARS COV2 has been strongly associated with gastrointestinal symptoms including nausea, vomiting, diarrhea, anorexia, loss ot taste and smell, and decreased saliva production. Tlie major gastrointestinal (Gl) signs include disordered hepatic synthetic function and transaminitis. We used data from 69 patients hospitalized with COVID-19 who are part of an ongoing observational, prospective COVID-19 study at the University of Mississippi Medical Center (UMMC) to determine how GI signs and symptoms correlated with mortality. Nausea (26%), vomiting (14%), and diarrhea (20%) were the primary GI symptoms at presentation. Overall mortality was lower in patients with one or more of these symptoms, as compared to those without symptoms on admission (36% vs 62%); although, any Cd presentation was found to significantly increase length of hospital stay. Abnormal hepatic transaminase levels were associated with both an increased length of stay (16% vs 84%) and increased mortality (11% vs 54%). Taken together, these preliminary data suggest that luminal GI symptoms in the setting of SARS COV2 in our patient population may be associated with a better outcome and that elevated serum transaminase levels may predict a worseningof mortality. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index