| Autor: |
López-Carrillo, Lizbeth, Mérida-Ortega, Ángel, Gómez-Ruiz, Humberto, Hernández-Garciadiego, Lucia, Gamboa-Loira, Brenda |
| Předmět: |
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| Zdroj: |
International Archives of Occupational & Environmental Health; May2021, Vol. 94 Issue 4, p699-706, 8p |
| Abstrakt: |
Objective: To evaluate the association between BC and urinary concentrations of free-bisphenol A (BPA-F), the biological form of BPA, among women residing in Northern Mexico. Methods: The population under study comprised 394 histologically confirmed BC cases and 404 age-matched controls. Women were interviewed face to face about their sociodemographic and reproductive characteristics. BPA-F was determined by high-pressure liquid chromatography equipped with a fluorescence detector (HPLC/FLD). Logistic regression models were used to estimate the adjusted BC risk in relation to BPA-F. Results: BPA-F geometric mean was significantly higher among cases compared to controls (3.16 μg/L in cases and 2.47 μg/L in controls). A significant adjusted BC odds ratio of 2.31 (95% CI: 1.43–3.74) was estimated for the highest category of BPA-F compared to the lowest category. Conclusion: BPA-F may be an environmental cofactor of BC. Since this is the first report on BPA-F association with BC, our results need to be replicated. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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