Neuro-meningeal cryptococcal infection revealing a multiple myeloma.

Autor: Sayhi, Sameh, Bouzidi, Sawsen, Beji, Imen, Allah Nasr, Aman, Hannachi, Souha, Bedoui, Ines, Layouni, Samy, Fekih-Mrissa, Najiba, Louzir, Bassem, Nsiri, Brahim, Abid, Rym, Battikh, Riadh
Zdroj: Pan African Medical Journal; May-Aug2020, Vol. 36, p1-7, 7p
Abstrakt: Rare cases of Cryptococcus have been documented in patients living with multiple myeloma. To date there has been no documented evidence of cryptococcosis revealing multiple myeloma. We reported a 63-year-old man who had a 2-months history continuous holocranial headaches, morning vomiting, complaining of blurred vision and fever. The biologic and the imaging showed a Cryptococcus meningoencephalitis. The search for a cause of immunodeficiency revealed a multiple myeloma. The diagnosis for Cryptococcus was confirmed according to an India ink stain, blood and cerebrospinal fluid culture. The patient's treatment for multiple myeloma was initiated with a chemotherapy regimen. The evolution was good without complication. Cryptococcosis, especially in the neuro-meningeal form, is a serious, deadly opportunistic infection. The search of an underlining immunodeficiency must be systematic. In this case, it was associated with early stage multiple myeloma. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index