| Autor: |
Giordano, F., Rossi, A., Pasquali, I., Bettini, R., Frigo, E., Gazzaniga, A., Sangalli, M. E., Mileo, V., Catinella, S. |
| Předmět: |
|
| Zdroj: |
Journal of Thermal Analysis & Calorimetry; 2003, Vol. 73 Issue 2, p509-518, 10p |
| Abstrakt: |
The thermal behaviour of Diclofenac was investigated using Differential Scanning Calorimetry, Hot Stage Microscopy, and Thermogravimetric Analysis. A discrepancy was observed between the melting point values recorded under dynamic flow of either dry nitrogen (180°C) or air (160°C). By means of High Performance Liquid Chromatography/Mass Spectrometric analyses, it has been possible to ascribe this difference in melting points to the formation of three degradation products as a result of intramolecular cyclization and condensation reactions during the heating process in an oxidative atmosphere. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
