PREVALENCE OF POSITIVE TROPONIN AND ECHOCARDIOGRAM IN PATIENTS WITH ACUTE ISCHEMIC STROKE FINDINGS AND THEIR ASSOCIATION WITH MORTALITY.

Autor: Mohiuddin, Khalid, Fayaz, Aidel, Shah, P. A., Bashir, Hamed
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Zdroj: JK Practitioner; Jan-Mar2021, Vol. 26 Issue 1/2, p5-9, 5p
Abstrakt: Introduction: Adverse cardiac events after stroke are associated with increased mortality. Current American Heart Association/American Stroke Association guidelines recommend evaluating cardiac biomarkers (preferably cardiac troponin [cTn]) in all patients presenting with acute ischemic stroke Objectives: Aim of current study was to analyze the prevalence of positive troponin levels and abnormal echocardiograph findings in patients admitted with acute ischemic stroke, and to analyse association of troponin levels with mortality rates in these patients. Results: Mortality rates were higher in patients with elevated troponin levels (23.3 % vs 8.4% in patients with trop > 14ng/l and trop <14nh/l respectively) with significant p value of 0.007. Non-fatal MI was higher in patients with elevated troponin levels (44.2 % vs 3.6% in patients with trop > 14ng/l and trop <14nh/l respectively). MACE rate was found in 13.9% patients with normal troponin levels and 39.5% patients with elevated troponin levels. During post discharge follow up, 11 6.6% patients who died from any cause had normal troponin levels as compared to 30.2% patients who had elevated troponin levels. The difference was found to be statistically significant (p < 0.05). Conclusion: Elevation of cTnT occurs in patients with acute ischemic stroke and can be regarded as a predictor of poor functional outcome and increased mortality. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index