| Autor: |
Hamoud, Hanan Raheem, Jabir Al-Kashwan, Thekra Abid, Tarish, Hashim Raheem |
| Předmět: |
|
| Zdroj: |
Magazine of Al-Kufa University for Biology; 2021, Vol. 13 Issue 1, p26-34, 9p |
| Abstrakt: |
Background: Some evidence has shown a relationship between human cytomegalovirus (HCMV) infection and pregnancy loss. However, whether recurrent or latent CMV infection or altered immune response to HCMV is related to recurrent pregnancy loss (RPL) is unclear. The recent study evaluated HCMV infection in women with RPL. Materials and Methods: The present case-control study was conducted on 100 women with RPL referred to Al-zahraa Teaching Hospital from April 2017 to July 2017 in Al-Najaf city (Iraq), and 100 women without a history of miscarriage were involved as controls. Patients and controls were undergone to an evaluation of anti-CMV IgG and IgM antibodies via Electro chemiluminescence (ECL) technology at Cobas e-411 analyzers (Roche Diagnostics /Germany). Chi-square test and student's t-test were used to analyze the data. Results: CMV infection was common among the study population. Anti-CMV IgG positivity was equal in patients and in controls (98.0% vs. 96.0%, P = 0.91), there was no difference between the two groups. Conclusion: The present study found that previous exposure to CMV was significantly higher in patients with RPL and in the control group. However, no association was found between IgG and RPL. Further investigations are needed to find whether latent CMV infection starts an indirect process of autoimmune etiology in RPL or women with RPL have recurrent or reactivation of CMV infection. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
