Drug-induced Liver Injury in a Patient With Coronavirus Disease 2019: Potential Interaction of Remdesivir With P-Glycoprotein Inhibitors.

Autor: Leegwater, Emiel, Strik, Anne, Wilms, Erik B, Bosma, Liesbeth B E, Burger, David M, Ottens, Thomas H, Nieuwkoop, Cees van
Předmět:
Zdroj: Clinical Infectious Diseases; Apr2021, Vol. 72 Issue 7, p1256-1258, 3p
Abstrakt: We report a case of a man with COVID-19 who developed acute hepatotoxicity related to remdesivir with probable interaction of P-glycoprotein (P-gp) inhibitors. Until further details on this interaction become available, we recommend physicians to be cautious with the prescription of P-gp inhibitors in patients receiving remdesivir therapy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index